Just download the dll, put it in system32 folder. Then from python:
from ctypes import windll
p = windll.inpout32
p.Inp32(0x378) #default 255(all high) on my pc
p.Out32(0x378, 0) #put all low on port 2-9
The address 0x378 might be different on your machine, open System->Hardware->Device Manager->Ports->ECP Printer Port->Properties->Resources, use the first number as your address.